Normal ranges are shown in parentheses

 

HAE-related laboratory results before starting C1-INH therapies:

 

• C1q level = 212 mcg/mL     (109-242 mcg/mL)

• C4 level = 7 mg/dL     (15-45 mg/dL; varies with lab)

• C1- INH level (C1-INH) level = 5 mg/dL     (16-33 mg/dL)

• C1-INH function = 10% of normal     (ELISA assay)

 

Note that complement studies for diagnosis must be performed when the patient is not receiving C1-INH replacement therapy because it will alter results.