Amy

• Amy is a 53-year-old woman diagnosed with Type I hereditary angioedema (HAE).

• She had her first attack at age 12, but was not diagnosed until age 39.

• In her late 30s, Amy experienced laryngeal attacks treated with epinephrine and continued to have laryngeal and abdominal swelling.

• Amy’s protracted history of HAE demonstrates the multiple factors that contribute to disease burden and can diminish QoL (1).

• Several years ago, she elected to undergo long-term prophylaxis.

•  Amy has been able to prevent attacks and assessments show that she now enjoys a considerably improved QoL.

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Family History

• Amy’s father and 2 sons have Type I HAE.

 

Comorbidities

• Rheumatoid arthritis

• Stage II hypertension

• Hypothyroidism

• Obesity

 

Current Medications

• Methotrexate 10 mg per week

• Levothyroxine 50 mcg QD

• Azilsartan medoxomil 80 mg QD

• Calcium supplement

• Long-term prophylaxis with subcutaneous
  kallikrein inhibitor